基因人源化

小鼠因其与人类基因组99%的相似性以及生理、生化指标的相似,已经成为使用最广泛的临床前药物评价模型及疾病模型之一。虽然二者基因组有着极其高度的相似性,但是某些蛋白的功能结构域,例如受体与供体结合位点,在小鼠和人之间仍然可能存在差异。另外,研究发现,某些人源基因在小鼠中也缺少同源基因。因此,在小鼠模型上对靶向这类人源蛋白的大分子药物进行临床前评价时,需要构建该类蛋白(基因)人源化的小鼠模型。

集萃药康的基因人源化小鼠模型,涵盖肿瘤、自免疾病领域,了解小鼠模型更多信息,请点击相应小鼠品系编号。

品系编号 靶点 品系简称 应用领域

T009882

VTCN1

BALB/c-hVTCN1

肿瘤

T009880

VTCN1

B6-hVTCN1

肿瘤

T059647

VSIG4

BALB/c-hVSIG4

肿瘤

T014757

VISTA

BALB/c-hVISTA

肿瘤

T054677

VEGFD

B6-hVEGFD

肿瘤

T055634

VEGFC

BALB/c-hVEGFC

肿瘤

T055633

VEGFB

BALB/c-hVEGFB

肿瘤

T054634

VEGFB

B6-hVEGFB

肿瘤

T059100

VEGFA/VEGFR2

BALB/c-hVEGFA/hVEGFR2

肿瘤

T017804

VEGFA

NCG-hVEGFA

肿瘤

T017803

VEGFA

BALB/c-hVEGFA

肿瘤

T054082

TSLPR

BALB/c-hTSLPR

自免疾病

T059652

TSLP/TSLPR

BALB/c-hTSLP/hTSLPR

自免疾病

T054084

TSLP

BALB/c-hTSLP

自免疾病

T056432

TROP2

BALB/c-hTROP2

肿瘤

T058949

TREM2

BALB/c-hTREM2

肿瘤

T056008

TREM2

B6-hTREM2

肿瘤

T064513

TREM1

BALB/c-hTREM1

肿瘤

T054534

TPSAB1

BALB/c-hTPSAB1

自免疾病

T055353

TPOR

BALB/c-hTPOR

肿瘤

T058456

TNFR2

BALB/c-hTNFR2

肿瘤

T037079

TNFR2

BALB/c-hPD1/hTNFR2

肿瘤

T055369

TNFR2

BALB/c-hPD1/hPDL1/hTNFR2

肿瘤

T054186

TLR8

BALB/c-hTLR8

自免疾病

T054187

TLR8

B6-hTLR8

自免疾病

T054553

TLR7

BALB/c-hTLR7

肿瘤

T054552

TLR7

B6-hTLR7

肿瘤

T055182

TLR3

BALB/c-hTLR3

自免疾病

T056526

TLR2

BALB/c-hTLR2

肿瘤

T003894

TIM3

BALB/c-hTIM3

肿瘤

T004795

TIM3

BALB/c-hPD1/hTIM3

肿瘤

T007059

TIM3

BALB/c-hPD1/hPDL1/hTIM3

肿瘤

T009737

TIM3

B6-hPD1/hTIM3

肿瘤

T058266

TIGIT/PVRIG

BALB/c-hTIGIT/hPVRIG

肿瘤

T059704

TIGIT/PVRIG

BALB/c-hPD1/hPDL1/hTIGIT/hPVRIG

肿瘤

T056729

TIGIT/OX40

BALB/c-hTIGIT/hOX40

肿瘤

T055241

TIGIT/CTLA4

BALB/c-hTIGIT/hCTLA4

肿瘤

T054842

TIGIT/CD96

BALB/c-hPD1/hPDL1/hTIGIT/hCD96

肿瘤

T054841

TIGIT/CD226

BALB/c-hPD1/hPDL1/hTIGIT/hCD226

肿瘤

T059258

TIGIT/CD155

BALB/c-hTIGIT/hCD155

肿瘤

T003365

TIGIT

BALB/c-hTIGIT

肿瘤

T004023

TIGIT

BALB/c-hPD1/hTIGIT

肿瘤

T051156

TIGIT

BALB/c-hPD1/hPDL1/hTIGIT/hCTLA4

肿瘤

T037004

TIGIT

BALB/c-hPD1/hPDL1/hTIGIT

肿瘤

T003366

TIGIT

B6-hTIGIT

肿瘤

T004024

TIGIT

B6-hPD1/hTIGIT

肿瘤

T006873

TIGIT

B6-hPD1/hPDL1/hTIGIT

肿瘤

T064267

TGFR2

B6-hTGFR2

肿瘤

T054838

TGFB2

BALB/c-hTGFB2

肿瘤

T054837

TGFB1

BALB/c-hTGFB1

肿瘤

T055118

TFRC(TfR1)

BALB/c-hTFRC(hTfR1)

肿瘤

T054281

TDO2

B6-hTDO2

肿瘤

T054362

TACSTD2(TROP2)

NCG-hTACSTD2(TROP2)

肿瘤

T055359

TACI

BALB/c-hTACI

自免疾病

T056080

SSTR2

BALB/c-hSSTR2

肿瘤

T050194

SIRPα

BALB/c-hPD1/hPDL1/hSIRPα

肿瘤

T004615

SIRPα

B6-hSIRPα

肿瘤

T006929

SIRPα

B6-hPD1/hSIRPα

肿瘤

T036819

SIRPA

B6-hPD1/hPDL1/hSIRPA

肿瘤

T037008

SIGLEC9

BALB/c-hSIGLEC9

肿瘤

T037010

SIGLEC9

BALB/c-hPD1/hPDL1/hSIGLEC9

肿瘤

T015774

SIGLEC9

B6-hSIGLEC9

肿瘤

T037340

SIGLEC9

B6-hPD1/hPDL1/hSIGLEC9

肿瘤

T058950

SIGLEC8

BALB/c-hSIGLEC8

肿瘤

T058257

SIGLEC7/SIGLEC9

B6-hSIGLEC7/hSIGLEC9

肿瘤

T057695

SIGLEC6

BALB/c-hSIGLEC6

肿瘤

T037094

SIGLEC15

BALB/c-hPD1/hPDL1/hSIGLEC15

肿瘤

T014939

SIGLEC15

B6-hSIGLEC15

肿瘤

T037006

SIGLEC15

B6-hPD1/hPDL1/hSIGLEC15

肿瘤

T054093

SIGLEC10

BALB/c-hSIGLEC10

肿瘤

T056079

SEMA4D

BALB/c-hSEMA4D

肿瘤

T056875

SELPLG

BALB/c-hSELPLG

肿瘤

T055267

RSPO3

BALB/c-hRSPO3

肿瘤

T055266

RSPO1

BALB/c-hRSPO1

肿瘤

T054682

PVRIG

BALB/c-hPVRIG

肿瘤

T058209

PRDM1

B6-hPRDM1 Tg-mPRDM1 KO

肿瘤

T054136

PGFRB

B6-hPGFRB

肿瘤

T059340

PGFRA

B6-hPDGFRA

肿瘤

T055358

PE2R2

BALB/c-hPE2R2

肿瘤

T055357

PE2R1

BALB/c-hPE2R1

肿瘤

T003260

PDL1

BALB/c-hPDL1

肿瘤

T003455

PDL1

B6-hPDL1

肿瘤

T004025

PD1/PDL1

BALB/c-hPD1/hPDL1

肿瘤

T004022

PD1/PDL1

B6-hPD1/hPDL1

肿瘤

T002726

PD1

BALB/c-hPD1

肿瘤

T003095

PD1

B6-hPD1

肿瘤

T064369

OX40/OX40L

B6-hOX40/hOX40L

肿瘤

T050263

OX40

BALB/c-hPD1/hPDL1/hOX40

肿瘤

T003804

OX40

BALB/c-hPD1/hOX40

肿瘤

T004363

OX40

BALB/c-hOX40

肿瘤

T004421

OX40

B6-hPD1/hOX40

肿瘤

T002140

OX40

B6-hOX40

肿瘤

T014770

NT5E

BALB/c-hPDL1/hNT5E

肿瘤

T054080

NKp46

NOD-Scid-hNKp46

肿瘤

T054840

NKp46

BALB/c-hNKp46

肿瘤

T054839

NKp46

B6-hNKp46

肿瘤

T057642

NKp30/NKp44

BALB/c-Tg(hNKp30/hNKp44)

肿瘤

T054081

NKp30

NOD-Scid-hNKp30

肿瘤

T057502

NKG2A/NKG2C/NKG2D/NKG2E/NKG2F/CD94

BALB/c-hNKG2ACDEF -Tg

肿瘤

T054085

NECTIN-4

NCG-hNECTIN-4

肿瘤

T056430

NECTIN-4

BALB/c-hNECTIN-4

肿瘤

T056431

NECTIN-4

B6-hNECTIN-4

肿瘤

T036853

MSLN

NCG-hMSLN

肿瘤

T036851

MSLN

BALB/c-hMSLN

肿瘤

T058350

MICB005

B6-hMICB005

肿瘤

T064234

MET

B6-hMET

肿瘤

T055879

MASP2

BALB/c-hMASP2

自免疾病

T064509

MARCO

BALB/c-hMARCO

肿瘤

T057411

LTBR

BALB/c-hLTBR

自免疾病

T015882

LRRC32

B6-hLRRC32

肿瘤

T056083

LRRC15

BALB/c-hLRRC15

肿瘤

T059590

LRRC15

B6-hLRRC15

肿瘤

T058104

LILRB1/LILRB2/LILRB3/LILRB4/LILRB5

BALB/c-hLILRB1/hLILRB2/hLILRB3/hLILRB4/hLILRB5

肿瘤

T055265

LGR6

BALB/c-hLGR6

肿瘤

T055264

LGR5

BALB/c-hLGR5

肿瘤

T055501

LAG3/TIGIT

BALB/c-hPD1/hPDL1/hLAG3/hTIGIT

肿瘤

T054544

LAG3/hFGL1

BALB/c-hLAG3/hFGL1

肿瘤

T037005

LAG3

BALB/c-hPD1/hPDL1/hLAG3

肿瘤

T004622

LAG3

BALB/c-hPD1/hLAG3

肿瘤

T007083

LAG3

BALB/c-hLAG3

肿瘤

T006876

LAG3

B6-hPD1/hPDL1/hLAG3

肿瘤

T004621

LAG3

B6-hPD1/hLAG3

肿瘤

T003597

LAG3

B6-hLAG3

肿瘤

T037679

KLRK1(NKG2D)

B6-hKLRK1(NKG2D)

肿瘤

T054645

KLRB1

BALB/c-hKLRB1

肿瘤

T057243

ITGAL

BALB/c-hITGAL

肿瘤

T056650

ITGA4/ITGB7(α4β7)

BALB/c-hITGA4/ITGB7(hα4β7)

自免疾病

T054083

IL7R

BALB/c-hIL7R

自免疾病

T054536

IL6R

BALB/c-hIL6R

自免疾病

T059996

IL6/IL6R

BALB/c-hIL6/hIL6R

自免疾病

T054535

IL6

BALB/c-hIL6

自免疾病

T056325

IL36A/IL36R(IL1RL2)

BALB/c-hIL36A/hIL36R(hIL1RL2)

自免疾病

T054582

IL33

BALB/c-hIL33

自免疾病

T057691

IL31/IL31RA/OSMR(OSMRβ)

BALB/c-hIL31/hIL31RA/hOSMR(hOSMRβ)

自免疾病

T055877

IL2RB

BALB/c-hIL2RB

肿瘤

T036802

IL2RA

hIL2RA

肿瘤

T055629

IL2RA

BALB/c-hPD1/hPDL1/hIL2RA

肿瘤

T059715

IL2RA

BALB/c-hIL2RA

肿瘤

T054087

IL23A

BALB/c-hIL23A

自免疾病

T057412

IL22/IL22RA1/IL10RB

BALB/c-hIL22/hIL22RA1/hIL10RB

自免疾病

T054583

IL1RL1

BALB/c-hIL1RL1

自免疾病

T053556

IL1B/PD1

BALB/c-hIL1B/hPD1

肿瘤

T053555

IL1B

BALB/c-hIL1B

肿瘤

T053317

IL18R1/IL18RAP

BALB/c-hIL18R1/hIL18RAP

肿瘤

T053316

IL18R1/IL18RAP

B6-hIL18R1/hIL18RAP

肿瘤

T059646

IL17A/IL17F

BALB/c-hIL17A/hIL17F

自免疾病

T037029

IL17A

Rosa26-CAG-LSL-hIL17A-IRES-EGFP-PolyA

自免疾病

T004291

IL17A

DBA-hIL17A

自免疾病

T003277

IL17A

BALB/c-hIL17A

自免疾病

T054123

IL13RA1

BALB/c-hIL13RA1

自免疾病

T054122

IL13

BALB/c-hIL13

自免疾病

T053352

IL12RB2

BALB/c-hIL12RB2

自免疾病

T058664

IL12RB1/hIL12RB2

BALB/c-hIL12RB1/hIL12RB2

自免疾病

T053318

IL12RB1

BALB/c-hIL12RB1

自免疾病

T058920

IL12B/IL23A

BALB/c-hIL12B/hIL23A

自免疾病

T058919

IL12B/IL12A

BALB/c-hIL12B/hIL12A

自免疾病

T054270

IL12B

BALB/c-hIL12B

自免疾病

T054269

IL12A

BALB/c-hIL12A

自免疾病

T057413

IL10/IL10RA/IL10RB

BALB/c-hIL10/hIL10RA/hIL10RB

自免疾病

T056195

IGHA1

B6-hIGHA1

自免疾病

T056078

IGF1R

BALB/c-IGF1R

肿瘤

T054201

IDO2

B6-hIDO2

肿瘤

T054200

IDO1

B6-hIDO1

肿瘤

T059642

ICAM1

BALB/c-hICAM1

肿瘤

T054543

HSA

BALB/c-HSA

肿瘤

T049869

HRAS

BALB/c;B6-Tg(hHRAS)

致癌性评价

T057193

HLA-DR4

BALB/c-hHLA-DR4

肿瘤

T056828

HLA-DR1

BALB/c-hHLA-DR1

抗原呈递

T064364

HLA-A24.2

BALB/c-hHLA-A24.2/hB2M

人源化MHC

T060170

HLA-A24.2

B6-hHLAA24.2/B2M

人源化MHC

T059101

HLA-A2.1/B2M

BALB/c-hHLAA2.1/B2M

抗原呈递

T064344

HLA-A2.1

B6-hHLA-A2.1/hB2M

人源化MHC

T060169

HLA-A11.1

BALB/c-hHLAA11.1/B2M

人源化MHC

T064359

HLA-A11.1

B6-hHLA-A11.1/hB2M

人源化MHC

T055184

HIF1A

BALB/c-hHIF1A

肿瘤

T009813

HER2

NCG-hHER2

肿瘤

T009819

HER2

BALB/c-hHER2-tg

肿瘤

T057039

HER2

BALB/c-hHER2

肿瘤

T055360

GPRC5D

BALB/c-hGPRC5D

肿瘤

T057416

GPR35

B6-hGPR35

肿瘤

T054198

GPC3

BALB/c-hGPC3

肿瘤

T053839

GPA33

NCG-hGPA33

肿瘤

T053837

GPA33

BALB/c-hGPA33

肿瘤

T004061

GITR

BALB/c-hPD1/hGITR

肿瘤

T054492

FLT4(VEGFR3)

B6-hFLT4(VEGFR3)

肿瘤

T054196

FLT3

BALB/c-hFLT3

肿瘤

T056654

FLT3

B6-FLT3-ITD

肿瘤

T055885

FGL2

BALB/c-hFGL2

肿瘤

T055886

FGL2

B6-hFGL2

肿瘤

T006214

FcRn

B6-hFcRn

药代动力学评价

T057759

FCGRT/ALB

B6-hALB/hFCGRT

药代动力学评价

T058881

FcgRs/PD1/CTLA4

BALB/c-hFcgRs-TG/hPD1/hCTLA4/mFcgRs-KO

药代动力学评价

T054592

FcgRs/CTLA4

BALB/c-hPD1/hCTLA4/hFcgRs

药代动力学评价

T055268

FcgRs/CD47/SIRPa

BALB/c-hCD47/hSIRPa/hFcgRs

药代动力学评价

T054095

FcgRs/CD137

BALB/c-hCD137/hFcgRs

药代动力学评价

T054094

FcgRs

NOD-Scid-hFcgRs

药代动力学评价

T059159

FcgRs

BALB/c-Tg-hFcgRs-KO-mFcgRs

药代动力学评价

T053273

FcgRs

BALB/c-FcgRs KO

药代动力学评价

T060133

FAP

Humanized FAP

肿瘤

T060378

FAD4T

NCG-FAD4T

肿瘤

T058085

ENPP1

BALB/c-hENPP1

肿瘤

T009811

EGFR

NCG-hEGFR

肿瘤

T009817

EGFR

BALB/c-hEGFR

肿瘤

T064257

EBI3

B6-hEBI3

肿瘤

T059103

DRA01-DRB10901

NCG-hDRA01-hDRB10901

肿瘤

T054646

Dr5(TNFRSF10B)

BALB/c-hDr5(TNFRSF10B)

肿瘤

T055631

DLL4

B6-hDLL4

肿瘤

T057818

DLK1

BALB/c-hDLK1

肿瘤

T056326

DLK1

B6-hDLK1

肿瘤

T056652

DDR1

B6-hDDR1

肿瘤

T055127

CXCR6

BALB/c-hCXCR6

肿瘤

T055271

CXCR4

BALB/c-hCXCR4

肿瘤

T059095

CXCR3

BALB/c-hCXCR3

肿瘤

T056874

CXCR2

BALB/c-hCXCR2

肿瘤

T057029

CTLA4/SIRPa

B6-hCTLA4/hSIRPa

肿瘤

T064418

CTLA4/CD47/SIRPα

BALB/c-hCTLA4/hCD47/hSIRPα

肿瘤

T007058

CTLA4

BALB/c-hPD1/hPDL1/hCTLA4

肿瘤

T003720

CTLA4

BALB/c-hPD1/hCTLA4

肿瘤

T003361

CTLA4

BALB/c-hCTLA4

肿瘤

T003826

CTLA4

B6-hPD1/hCTLA4

肿瘤

T003362

CTLA4

B6-hCTLA4

肿瘤

T054550

CSF2RB

B6-hCSF2RB

肿瘤

T057788

CSF2/IL3

BALB/c-hCSF2/hIL3

肿瘤

T054272

CSF2(GMCSF)

DBA-hCSF2(GMCSF)

自免疾病

T054271

CSF2(GMCSF)

BALB/c-hCSF2(GMCSF)

自免疾病

T015766

CSF1R

BALB/c-hPDL1/hCSF1R

肿瘤

T006213

CSF1R

B6-hPD1/hCSF1R

肿瘤

T014759

CSF1R

B6-hCSF1R

肿瘤

T036902

CSF1

B6-hCSF1

肿瘤

T055714

CS1

BALB/c-hCS1

肿瘤

T057241

CRBN

BALB/c-hCRBN

肿瘤

T054279

CLL1

BALB/c-hCLL1

肿瘤

T054643

CLEC5A

BALB/c-hCLEC5A

肿瘤

T059696

CLEC4C

BALB/c-hCLEC4C

自免疾病

T055716

CLEC14A

BALB/c-hCLEC14A

肿瘤

T057501

CEACAM6

BALB/c-hCEACAM6

肿瘤

T059591

CEACAM5

BALB/c-hCEACAM5(BAC-Tg)

肿瘤

T058753

CEACAM5

B6-hCEACAM5(BAC-Tg)

肿瘤

T058628

CD98hc

BALB/c-hPD1/hPDL1/hCD98hc

肿瘤

T060056

CD98hc

B6-hCD98HC

肿瘤

T054647

CD93

BALB/c-hCD93

肿瘤

T059256

CD9

BALB/c-hCD9

肿瘤

T054190

CD80

BALB/c-hCD80

自免疾病

T058947

CD79

BALB/c-hCD79a/hCD79b

肿瘤

T054480

CD74

BALB/c-hCD74

肿瘤

T058749

CD73/CD39

BALB/c-hPD1/hPDL1/hCD73/hCD39

肿瘤

T036652

CD73

BALB/c-hPD1/hPDL1/hCD73

肿瘤

T009410

CD73

B6-hPD1/hPDL1/hCD73

肿瘤

T014695

CD73

B6-hCD73

肿瘤

T055129

CD70

BALB/c-hCD70

肿瘤

T059463

CD7

BALB/c-hCD7

肿瘤

T055016

CD69

BALB/c-hCD69

肿瘤

T059096

CD6

BALB/c-hCD6

肿瘤

T055884

CD52

BALB/c-hCD52

肿瘤

T057924

CD5

BALB/c-hCD5

肿瘤

T056521

CD5

B6-hCD5

肿瘤

T050195

CD47/SIRPα

BALB/c-hPD1/hPDL1/hCD47/hSIRPA

肿瘤

T037264

CD47/SIRPα

BALB/c-hCD47/hSIRPα

肿瘤

T037007

CD47/SIRPα

B6-hCD47/hSIRPα

肿瘤

T005313

CD47

BALB/c-hPD1/hCD47

肿瘤

T014646

CD47

BALB/c-hCD47

肿瘤

T036820

CD47

B6-hPD1/hPDL1/hCD47

肿瘤

T004666

CD47

B6-hPD1/hCD47

肿瘤

T007666

CD47

B6-hCD47

肿瘤

T064265

CD46

B6-hCD46

肿瘤

T056011

CD44v6

BALB/c-hCD44v6

肿瘤

T056010

CD44

BALB/c-hCD44

肿瘤

T055018

CD40

BALB/c-hPD1/hPDL1/hCD40

肿瘤

T051430

CD40

BALB/c-hCD40

肿瘤

T036974

CD39

BALB/c-hPD1/hPDL1/hCD39

肿瘤

T057786

CD38

BALB/c-hPD1/hPDL1/CD38

肿瘤

T060262

CD38

BALB/c-hCD38

肿瘤

T054000

CD38

B6-hCD38

肿瘤

T056429

CD34

B6-hCD34

肿瘤

T054092

CD30

BALB/c-hCD30

肿瘤

T050041

CD3/MSLN

BALB/c-hCD3E/hMSLN

肿瘤

T017537

CD3/KDR

BALB/c-hCD3E/hKDR

肿瘤

T058817

CD3/GPRC5D

BALB/c-hGPRC5D/hCD3EDG

肿瘤

T053838

CD3/GPA33

BALB/c-hCD3E/hGPA33

肿瘤

T057420

CD3/CD73

BALB/c-hCD73/hCD3EDG

肿瘤

T057819

CD3/CD5

BALB/c-hCD3/hCD5

肿瘤

T057544

CD3/CD28

BALB/c-hCD3EDG/hCD28

肿瘤

T009031

CD3

BALB/c-Tg(hCD3EDG)

肿瘤

T053483

CD3

BALB/c-hCD3EDG

肿瘤

T001550

CD3

BALB/c-hCD3E

肿瘤

T054368

CD3

B6-mCD3EDG-KO

肿瘤

T064461

CD3

B6-hCD3EDG [BAC]

肿瘤

T064289

CD3

B6-CD3EDG

肿瘤

T014895

CD28

hCD28

肿瘤

T064376

CD28

BALB/c-hCD28

肿瘤

T004279

CD28

B6-hPD1/hCD28

肿瘤

T057467

CD276(B7-H3)

BALB/c-hPDL1/hCD276

肿瘤

T056502

CD276(B7-H3)

BALB/c-hCD276

肿瘤

T057466

CD276(B7-H3)

B6-hPDL1/hCD276

肿瘤

T056501

CD276(B7-H3)

B6-hCD276

肿瘤

T053821

CD27

BALB/c-hPD1/hPDL1/hCD27

肿瘤

T037422

CD27

BALB/c-hPD1/hCD27

肿瘤

T055128

CD27

BALB/c-hCD27

肿瘤

T006778

CD27

B6-hPD1/hCD27

肿瘤

T059695

CD24/Siglec10

BALB/c-hCD24/hSIGLEC10

肿瘤

T054140

CD24

BALB/c-hCD24

肿瘤

T064282

CD24

B6-hCD24-CKO

肿瘤

T064459

CD24

B6-hCD24

肿瘤

T054581

CD228(MELTF)

NCG-hCD228(MELTF)

肿瘤

T058940

CD22

BALB/c-hCD3EDG/hCD22

肿瘤

T054197

CD22

BALB/c-hCD22

肿瘤

T053698

CD22

B6-hCD22

自免疾病

T057498

CD20

BALB/c-hCD20-tg

肿瘤

T054538

CD138

NCG-hCD138

肿瘤

T054537

CD138

BALB/c-hCD138

肿瘤

T064372

CD137/CD40

BALB/c-hCD137/hCD40

肿瘤

T007056

CD137

BALB/c-hPD1/hPDL1/hCD137

肿瘤

T004005

CD137

BALB/c-hPD1/hCD137

肿瘤

T003359

CD137

BALB/c-hCD137

肿瘤

T057201

CD137

B6-hPD1/hPDL1/hCD137

肿瘤

T004082

CD137

B6-hPD1/hCD137

肿瘤

T003360

CD137

B6-hCD137

肿瘤

T054365

CD125

B6-hIL5RA(CD125)

肿瘤

T056327

CCR2

BALB/c-hCCR2

肿瘤

T055882

CA9

B6-hCA9

肿瘤

T056196

C3

B6-hC3

自免疾病

T059683

BTLA

BALB/c-hPD1/PDL1/BTLA

肿瘤

T006779

BTLA

BALB/c-hBTLA

肿瘤

T004138

BTLA

BALB/c-hPD1/hBTLA

肿瘤

T059045

BCMA

BALB/c-hCD3EDG/hBCMA

肿瘤

T054078

BCMA

BALB/c-hBCMA

肿瘤

T036794

BAFF

B6-hBAFF

自免疾病

T055999

ANGPT2

BALB/c-hANGPT2

肿瘤

T055883

ANG

B6-hANG

肿瘤

T054124

ALK

NCG-hALK

肿瘤

T060135

ALCAM

BALB/c-hALCAM

肿瘤

T056761

ADAM17

BALB/c-hADAM17

肿瘤

T055126

A2aR

BALB/c-hA2aR

肿瘤

T004081

BTLA

B6-hPD1/hBTLA

肿瘤

T003585